Diphtheria

Homepage for CDC's information on diphtheria.

This content is for informational purposes only. Always consult a healthcare professional.

Source: Centers for Disease Control and Prevention — Content from the Centers for Disease Control and Prevention (public domain).

Image of a doctor examining the throat of a young child with a tongue depressor.

About

Learn about diphtheria: types, cause, risk factors, treatment, and prevention.

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May 12, 2025

Doctor examining adult male patient

Symptoms and Complications

Respiratory diphtheria causes more serious symptoms and disease than diphtheria skin infections.

May 12, 2025

A picture of a multi-generational family.

Vaccination

People of all ages should get vaccinated against diphtheria.

May 12, 2025

Healthcare providers

Child with cervical swelling, referred to as bull neck, which is a symptom of diphtheria.

Clinical Overview

Diphtheria is an acute disease that’s rare in the United States.

May 12, 2025

Diagnosis and treatment

* [Clinical Features](</diphtheria/hcp/clinical-signs/index.html>)

Respiratory and cutaneous diphtheria are the most common disease presentations.

* [Clinical Guidance](</diphtheria/hcp/clinical-guidance/index.html>)

Information on diagnosis, testing, treatment, and prevention of diphtheria.

* [Diphtheria Antitoxin (DAT)](</diphtheria/hcp/dat/index.html>)

CDC can distribute diphtheria antitoxin (DAT) to healthcare providers to treat diphtheria.

Public health professionals

An illustration of generic data

Surveillance and Trends

CDC tracks diphtheria cases nationally. Diphtheria is now an uncommon disease in the United States.

May 12, 2025

Corynebacterium diphtheriae on an Elek plate.

Lab Testing

CDC has the only U.S. laboratory that performs specialized testing to confirm diphtheria diagnoses.

May 12, 2025

Diphtheria bacteria growing on a Tinsdale plate.

Pertussis and Diphtheria Lab

CDC has a laboratory focused on innovative research related to pertussis and diphtheria.

Apr. 2, 2024

⚠ Caution
Medical Disclaimer: This information is for educational purposes only. Always consult a healthcare professional for medical advice.